#46: She Gives a Late-Career Performance as Sara Goldfarb in Requiem for a Dream in 2000
In 2000, she gave one of her most intense late-career performances as Sara Goldfarb in Darren Aronofsky’s Requiem for a Dream. Sara was a lonely Brooklyn widow who becomes fixated on appearing on television and then falls into addiction through prescribed diet pills.

The role required physical transformation, emotional exposure, and a painful portrait of isolation. It showed that she could still take risks decades after her 1970s peak. The performance was difficult to watch, but it reminded audiences how fearless she could be.
