#48: She Calls the Performance Her Best Acting Achievement
In an interview with Charlie Rose, she stated that playing Sara Goldfarb in Requiem for a Dream was, in her opinion, her best acting achievement. That was a striking choice from an actress whose career already included The Exorcist, Alice Doesn’t Live Here Anymore, and multiple Oscar-nominated roles.

The comment showed how deeply she valued the part. Sara required vulnerability, physical transformation, loneliness, and emotional collapse, all compressed into one painful portrait. Even after decades of acclaimed work, this was the performance she singled out.
